Groundbreaking Breakthrough Offers Hope for Women Struggling with Age-Related Infertility
Scientists in Germany have made a major breakthrough in understanding the underlying cause of age-related female infertility, which has long plagued many women attempting to conceive through IVF. A study presented at the Fertility 2026 conference in Edinburgh suggests that an age-defecting protein, called Shugoshin 1, can be supplemented to improve egg quality.
For years, women over 35 have faced declining success rates with IVF due to the natural deterioration of their eggs. This decline has led to a rollercoaster of emotions for those undergoing treatment, ranging from hope and joy to despair and disappointment. The current lack of effective solutions has left many feeling like they're stuck in an endless cycle of failed pregnancies.
However, research conducted by scientists at Ovo Labs has shed new light on this issue. They discovered that the presence or absence of Shugoshin 1 protein plays a crucial role in maintaining egg health as women age. The lack of sufficient Shugoshin 1 enables chromosomes to fray apart during fertilization, leading to defective embryos.
A recent study demonstrated that supplementing eggs with Shugoshin 1 reduces the likelihood of this defect by nearly half. While still experimental and requiring further testing, this breakthrough holds great promise for improving IVF success rates.
Researchers believe that timing is crucial in addressing this age-related defect. Eggs could be rejuvenated through a microinjection procedure between harvesting and fertilizing them, potentially increasing conception rates within a single attempt. This approach has the potential to significantly reduce the emotional burden associated with failed pregnancies, making the IVF journey more manageable for those struggling.
As the research advances, it's essential to exercise caution and not get ahead of ourselves. The Ovo Labs team acknowledges that more time is needed to confirm safety and efficacy before making any promises. Nonetheless, this breakthrough offers a beacon of hope in an otherwise daunting landscape of infertility struggles.
The potential benefits of this discovery cannot be overstated. By tackling the root cause of age-related female infertility, we may soon see a significant increase in successful IVF pregnancies. As Dr. Agata Zielinska from Ovo Labs so aptly put it, "Our aim is to really reduce the time to successful conception... Many more women would be able to conceive within a single IVF attempt."
Scientists in Germany have made a major breakthrough in understanding the underlying cause of age-related female infertility, which has long plagued many women attempting to conceive through IVF. A study presented at the Fertility 2026 conference in Edinburgh suggests that an age-defecting protein, called Shugoshin 1, can be supplemented to improve egg quality.
For years, women over 35 have faced declining success rates with IVF due to the natural deterioration of their eggs. This decline has led to a rollercoaster of emotions for those undergoing treatment, ranging from hope and joy to despair and disappointment. The current lack of effective solutions has left many feeling like they're stuck in an endless cycle of failed pregnancies.
However, research conducted by scientists at Ovo Labs has shed new light on this issue. They discovered that the presence or absence of Shugoshin 1 protein plays a crucial role in maintaining egg health as women age. The lack of sufficient Shugoshin 1 enables chromosomes to fray apart during fertilization, leading to defective embryos.
A recent study demonstrated that supplementing eggs with Shugoshin 1 reduces the likelihood of this defect by nearly half. While still experimental and requiring further testing, this breakthrough holds great promise for improving IVF success rates.
Researchers believe that timing is crucial in addressing this age-related defect. Eggs could be rejuvenated through a microinjection procedure between harvesting and fertilizing them, potentially increasing conception rates within a single attempt. This approach has the potential to significantly reduce the emotional burden associated with failed pregnancies, making the IVF journey more manageable for those struggling.
As the research advances, it's essential to exercise caution and not get ahead of ourselves. The Ovo Labs team acknowledges that more time is needed to confirm safety and efficacy before making any promises. Nonetheless, this breakthrough offers a beacon of hope in an otherwise daunting landscape of infertility struggles.
The potential benefits of this discovery cannot be overstated. By tackling the root cause of age-related female infertility, we may soon see a significant increase in successful IVF pregnancies. As Dr. Agata Zielinska from Ovo Labs so aptly put it, "Our aim is to really reduce the time to successful conception... Many more women would be able to conceive within a single IVF attempt."