People who are using the medication Ozempic to lose weight have been losing muscle mass and feeling weak, which is causing concern among health experts. The drug, also known as semaglutide, works by slowing down digestion and telling the brain that it's full, making it easier for people to eat less. However, some patients taking the medication are experiencing significant loss of muscle mass and functional strength.
Dr. Robert Lustig, a metabolic scientist at the University of California-San Francisco, says that GLP-1 drugs like Ozempic are not a magic solution, but rather a Band-Aid that addresses the symptoms of obesity rather than the underlying causes. "It's not sufficient," he says. "We need to treat the underlying issue with healthy eating and exercise."
In clinical trials, patients taking semaglutide have lost significant weight, but many also experience muscle loss or weakness. One study found that about 40% of patients losing weight on semaglutide were losing important muscle mass.
Experts warn that taking GLP-1 drugs without making lifestyle changes can lead to malnutrition and weakened muscles. "If you don't change your behavior, if you don't change your habits, you may be looking good, you may be losing weight, but metabolically, your body is in turmoil," says Nayan Patel, a pharmacist.
To make the most of GLP-1s, experts recommend eating a high-protein diet with plenty of amino acids and strength training. "Eating protein and strength training allows your body to be more effective at trimming the fat, without compromising your core strength," Patel says.
The FDA has warned that patients taking semaglutide should also follow a low-carb diet and engage in regular exercise, including weight training and stretching exercises.
Dr. Robert Lustig, a metabolic scientist at the University of California-San Francisco, says that GLP-1 drugs like Ozempic are not a magic solution, but rather a Band-Aid that addresses the symptoms of obesity rather than the underlying causes. "It's not sufficient," he says. "We need to treat the underlying issue with healthy eating and exercise."
In clinical trials, patients taking semaglutide have lost significant weight, but many also experience muscle loss or weakness. One study found that about 40% of patients losing weight on semaglutide were losing important muscle mass.
Experts warn that taking GLP-1 drugs without making lifestyle changes can lead to malnutrition and weakened muscles. "If you don't change your behavior, if you don't change your habits, you may be looking good, you may be losing weight, but metabolically, your body is in turmoil," says Nayan Patel, a pharmacist.
To make the most of GLP-1s, experts recommend eating a high-protein diet with plenty of amino acids and strength training. "Eating protein and strength training allows your body to be more effective at trimming the fat, without compromising your core strength," Patel says.
The FDA has warned that patients taking semaglutide should also follow a low-carb diet and engage in regular exercise, including weight training and stretching exercises.