Weight Loss Jabs May Need Long-Term Commitment for Sustainable Results
A new study has found that patients who stop using Mounjaro, a weight loss medication containing tirzepatide, do not just regain weight but also experience a reversal of other health benefits. The research, published in the journal Jama Internal Medicine, suggests that sustained weight management is crucial to maintain cardiometabolic benefits and improved quality of life.
Participants in the Surmount-4 trial who lost at least 10% of their body weight after 36 weeks on tirzepatide were randomly split into two groups. One group continued the medication for another 52 weeks, while the other switched to a placebo. The study found that one year after stopping tirzepatide, nearly 82% of participants had regained at least 25% of their initial weight loss.
Moreover, greater weight regain was associated with a reversal of improvements in waist circumference, levels of "bad" cholesterol, blood pressure, and blood glucose levels. By the end of the study, those who had regained more than 75% of their original weight showed a complete reversal of cardiometabolic parameters to baseline values.
Experts warn that stopping weight loss jabs can remove protective effects against heart failure or death from any cause. Researchers also note that taking these medications does not guarantee healthier eating and exercise habits, as people may lose motivation once the medication is stopped.
Jane Ogden, an emeritus professor at the University of Surrey, pointed out that patients who stop using weight loss jabs tend to return to their previous behaviors, leading to a reversal in health benefits. She emphasized the importance of lifestyle interventions and obesity management medications for sustaining cardiometabolic benefits.
The study's findings support the notion that long-term maintenance of weight reduction is critical to maintaining overall health and well-being. As newer, more affordable strategies for supporting long-term weight loss maintenance emerge, it is essential for individuals to remain committed to healthy habits beyond their medication treatment.
A new study has found that patients who stop using Mounjaro, a weight loss medication containing tirzepatide, do not just regain weight but also experience a reversal of other health benefits. The research, published in the journal Jama Internal Medicine, suggests that sustained weight management is crucial to maintain cardiometabolic benefits and improved quality of life.
Participants in the Surmount-4 trial who lost at least 10% of their body weight after 36 weeks on tirzepatide were randomly split into two groups. One group continued the medication for another 52 weeks, while the other switched to a placebo. The study found that one year after stopping tirzepatide, nearly 82% of participants had regained at least 25% of their initial weight loss.
Moreover, greater weight regain was associated with a reversal of improvements in waist circumference, levels of "bad" cholesterol, blood pressure, and blood glucose levels. By the end of the study, those who had regained more than 75% of their original weight showed a complete reversal of cardiometabolic parameters to baseline values.
Experts warn that stopping weight loss jabs can remove protective effects against heart failure or death from any cause. Researchers also note that taking these medications does not guarantee healthier eating and exercise habits, as people may lose motivation once the medication is stopped.
Jane Ogden, an emeritus professor at the University of Surrey, pointed out that patients who stop using weight loss jabs tend to return to their previous behaviors, leading to a reversal in health benefits. She emphasized the importance of lifestyle interventions and obesity management medications for sustaining cardiometabolic benefits.
The study's findings support the notion that long-term maintenance of weight reduction is critical to maintaining overall health and well-being. As newer, more affordable strategies for supporting long-term weight loss maintenance emerge, it is essential for individuals to remain committed to healthy habits beyond their medication treatment.
I'm low-key freaking out about this new study on weight loss jabs 
Like, if you stop taking Mounjaro after using it for 36 weeks, your body just goes back to normal, right? 
It's like, a total reversal of all the good stuff you got going on! 
It's like, we need to be super committed to our fitness goals and eating habits even when the medication is gone! 
I know, I know, it sounds hard, but trust me, it's worth it! 
So, who's with me on making healthy choices for life? 
. Newsflash: you can't just tweet your way to a healthy lifestyle, you gotta put in the work! 
And let's be real, weight loss meds are like campaign promises – they sound great at first, but what happens when you're not re-elected (i.e., you stop taking them)? 
The experts are saying we need more than just medication, we need a comprehensive plan for maintaining healthy habits. It's time to get serious about building a 'sustainable' lifestyle, folks! 
. I mean sure it would be awesome if meds could do all the work for us but honestly its better to get educated on how to take control of our own health 
and yeah, experts are right, no magic pill can replace healthy habits. we need more support and resources for people struggling to stick to it 
. It's like, you take it for a few months to get in shape, and then you just stop taking it and BAM! You're right back where you started 
. It's like they're not even worth it in the long run. And don't even get me started on how hard it is to maintain healthy habits without some sort of crutch 
.
it's like tryna quit smokin' and then go back 2 havin' a pack a day... not gonna happen 
gotta stay vigilant, stay committed. otherwise, u might as well 4get about all the good weight loss jabs did 4 u in the first place 
I'm not surprised by this study's findings. Weight loss meds are never a magic solution. They can be helpful in the short term, but once you stop taking them, it's all back to square one. It's like trying to build a house on quicksand - it'll look great for a bit, but eventually, it'll all come crashing down. I mean, we all know that eating healthy and exercising regularly is way more important than popping pills. But, at the same time, these meds can be a game-changer for people who really need them to get started on their weight loss journey. The thing is, we need to stop relying so much on medication and start focusing on sustainable lifestyle changes that'll actually stick in the long term. 
. It's all about finding that balance between progress and maintenance. We need to teach people how to make healthy habits stick beyond the initial weight loss buzz 
... and that takes time & effort 
! It's like they're just giving people a quick fix and expecting them to magically change their lifestyle 
. Newsflash: it doesn't work that way 
!
. We can't rely solely on meds to fix our health issues; we need to make sustainable lifestyle changes that become a habit 
. We need to educate people on the importance of healthy eating and exercise, and support them in making those habits stick 
.
